Lei Zhao Selected Research

Colorectal Neoplasms (Colorectal Cancer)

5/2024	Emodin induces ferroptosis in colorectal cancer through NCOA4-mediated ferritinophagy and NF-κb pathway inactivation.
1/2024	β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway.
12/2023	Transformation of Ginsenosides by Lactiplantibacillus plantarum MB11 Fermentation: Minor Ginsenosides Conversion and Enhancement of Anti-Colorectal Cancer Activity.
2/2023	The past, present, and future of immunotherapy for colorectal cancer.
1/2023	CEMIP, acting as a scaffold protein for bridging GRAF1 and MIB1, promotes colorectal cancer metastasis via activating CDC42/MAPK pathway.
1/2023	Tumor CEMIP drives immune evasion of colorectal cancer via MHC-I internalization and degradation.
1/2022	Targeting DCLK1 overcomes 5-fluorouracil resistance in colorectal cancer through inhibiting CCAR1/β-catenin pathway-mediated cancer stemness.
1/2022	Tumor Microenvironment Heterogeneity-Based Score System Predicts Clinical Prognosis and Response to Immune Checkpoint Blockade in Multiple Colorectal Cancer Cohorts.
1/2022	The long non-coding RNA T cell leukemia homeobox 1 neighbor enhances signal transducer and activator of transcription 5A phosphorylation to promote colon cancer cell invasion, migration, and metastasis.
11/2021	CEMIP, a novel adaptor protein of OGT, promotes colorectal cancer metastasis through glutamine metabolic reprogramming via reciprocal regulation of β-catenin.

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Lei Zhao Research Topics

Disease

311	Neoplasms (Cancer) 05/2024 - 10/2006
133	Inflammation (Inflammations) 04/2024 - 09/2002
63	Neoplasm Metastasis (Metastasis) 01/2024 - 12/2004
61	Infections 03/2024 - 04/2007
55	Fibrosis (Cirrhosis) 04/2024 - 02/2013
37	Hepatocellular Carcinoma (Hepatoma) 04/2024 - 12/2004
34	Cardiovascular Diseases (Cardiovascular Disease) 01/2024 - 09/2004
34	Esophageal Squamous Cell Carcinoma 11/2023 - 08/2012
34	Breast Neoplasms (Breast Cancer) 07/2023 - 06/2007
32	Carcinogenesis 10/2023 - 10/2009
32	Stomach Neoplasms (Stomach Cancer) 01/2023 - 03/2009
30	Insulin Resistance 04/2024 - 01/2009
30	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 02/2024 - 03/2009
29	Heart Failure 04/2024 - 01/2009
28	Colorectal Neoplasms (Colorectal Cancer) 05/2024 - 01/2012
28	Atherosclerosis 08/2023 - 09/2002
27	Obesity 09/2023 - 01/2009
24	COVID-19 03/2024 - 01/2020
21	Non-alcoholic Fatty Liver Disease 05/2024 - 01/2009
21	Periodontitis 03/2024 - 02/2008
20	Type 2 Diabetes Mellitus (MODY) 04/2024 - 12/2005
20	Alzheimer Disease (Alzheimer's Disease) 01/2024 - 12/2004
19	Hemorrhage 03/2024 - 01/2007
19	Carcinoma (Carcinomatosis) 01/2023 - 03/2009
18	Necrosis 01/2022 - 03/2006
17	Sepsis (Septicemia) 03/2024 - 05/2006
17	Stroke (Strokes) 02/2024 - 09/2004
16	Body Weight (Weight, Body) 12/2023 - 08/2011
16	Liver Cirrhosis (Hepatic Cirrhosis) 07/2023 - 10/2009
16	Hypoxia (Hypoxemia) 01/2023 - 12/2011
16	Brain Ischemia (Cerebral Ischemia) 01/2023 - 06/2008
15	Atrial Fibrillation 05/2024 - 01/2019
15	Wounds and Injuries (Trauma) 03/2024 - 03/2012
15	Ischemia 01/2023 - 06/2008
15	Pancreatic Neoplasms (Pancreatic Cancer) 01/2023 - 12/2009
14	Myocardial Infarction 11/2023 - 09/2004
13	Infarction (Infarctions) 03/2024 - 06/2008
13	Ischemic Stroke 02/2024 - 01/2015
13	Cognitive Dysfunction 10/2023 - 05/2010
13	Leukemia 10/2023 - 07/2010
13	Lung Neoplasms (Lung Cancer) 07/2023 - 03/2009
13	Reperfusion Injury 01/2020 - 06/2008
12	Pain (Aches) 04/2024 - 11/2006
12	Hypertension (High Blood Pressure) 01/2024 - 10/2009
12	Lymphoma (Lymphomas) 01/2023 - 04/2008
12	Esophageal Neoplasms (Esophageal Cancer) 01/2023 - 12/2013
12	Hyperuricemia 10/2022 - 01/2019
12	Colonic Neoplasms (Colon Cancer) 01/2022 - 10/2009
11	Virus Diseases (Viral Diseases) 03/2024 - 06/2014
11	Squamous Cell Carcinoma (Epidermoid Carcinoma) 03/2024 - 04/2009
11	Adenocarcinoma 11/2023 - 12/2011
11	Prostatic Neoplasms (Prostate Cancer) 01/2023 - 01/2015
10	Parkinson Disease (Parkinson's Disease) 02/2024 - 12/2007

Drug/Important Bio-Agent (IBA)

151	Proteins (Proteins, Gene)FDA Link 04/2024 - 01/2002
91	Biomarkers (Surrogate Marker)IBA 01/2024 - 10/2007
52	Messenger RNA (mRNA)IBA 02/2024 - 09/2002
43	MicroRNAs (MicroRNA)IBA 01/2024 - 05/2010
40	CytokinesIBA 01/2024 - 09/2002
33	Glucose (Dextrose)FDA LinkGeneric 04/2024 - 12/2005
33	Long Noncoding RNAIBA 02/2024 - 11/2015
31	LipidsIBA 04/2024 - 09/2004
28	LipopolysaccharidesIBA 03/2024 - 12/2005
27	EnzymesIBA 03/2024 - 07/2004
26	Therapeutic UsesIBA 04/2023 - 03/2009
25	Peptides (Polypeptides)IBA 04/2024 - 09/2002
25	Interleukin-6 (Interleukin 6)IBA 02/2023 - 05/2006
23	DNA (Deoxyribonucleic Acid)IBA 03/2024 - 04/2009
23	Immune Checkpoint InhibitorsIBA 02/2024 - 01/2020
21	CholesterolIBA 12/2023 - 01/2009
20	LigandsIBA 04/2024 - 07/2008
19	Phosphotransferases (Kinase)IBA 12/2020 - 07/2010
18	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2023 - 05/2006
17	Antiviral Agents (Antivirals)IBA 05/2022 - 11/2010
16	RNA (Ribonucleic Acid)IBA 05/2024 - 01/2011
15	Insulin (Novolin)FDA Link 04/2024 - 12/2005
15	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2024 - 12/2006
15	Cisplatin (Platino)FDA LinkGeneric 03/2024 - 03/2010
15	Fatty Acids (Saturated Fatty Acids)IBA 12/2023 - 01/2014
15	CateninsIBA 12/2023 - 12/2018
15	InterleukinsIBA 06/2023 - 08/2007
15	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 03/2010
14	Monoclonal AntibodiesIBA 05/2024 - 06/2007
14	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2023 - 01/2014
14	corilaginIBA 01/2023 - 07/2008
13	AntioxidantsIBA 04/2024 - 12/2005
13	C-Reactive ProteinIBA 01/2021 - 02/2007
12	InflammasomesIBA 05/2024 - 06/2017
12	AntibodiesIBA 03/2024 - 04/2008
12	Circular RNAIBA 06/2023 - 01/2019
11	CollagenIBA 04/2024 - 02/2013
11	CreatinineIBA 04/2024 - 11/2011
11	Amyloid (Amyloid Fibrils)IBA 01/2020 - 05/2010
10	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2024 - 01/2013

Therapy/Procedure

133	Therapeutics 12/2024 - 12/2004
55	Drug Therapy (Chemotherapy) 02/2024 - 11/2006
30	Immunotherapy 02/2024 - 05/2016
22	Radiotherapy 07/2023 - 01/2013
17	Neoadjuvant Therapy 05/2024 - 08/2015
14	Chinese Traditional Medicine (Traditional Chinese Medicine) 12/2024 - 10/2013
13	Chemoradiotherapy 01/2023 - 01/2014